Medicine

Antibiotics In Travelers Diarrhoea

ABSTRACT

Travellers’ diarrhea is the most common illness experienced by travellers and with an incidence estimated from 20% to over 80%. The occurrence of three or more unformed stools within a 24 hour period or any number of such unformed stools when accompanied by either nausea, vomiting, abdominal cramps, tenesmus (involuntary straining with little or no passage of fecal matter), or fever. Approximately 20 million episodes of diarrhea occur annually in people traveling from industrialized regions to budding countries. Diarrheogenic Escherichia coli, including enterotoxigenic E. coli and enteroaggregative E. coli, are responsible for ~50% of cases. The invasive bacterial pathogens are Shigella, Salmonella, invasive E. coli, and Campylobacter jejuni cause ~10–25% of cases, with the highest frequencies in southern Asia. A study revealed that 46 percent acquired diarrhea conditions are found in developing countries. Traveler’s diarrhea is more common in young children and has a privileged risk of dehydration and serious sickness. The drug of choice for most children with traveler’s diarrhea is Azithromycin. The main complication of traveler’s diarrhea is Dehydration. Bismuth Subsalicylate two tablets QID, which partly protective
against travelers’ diarrhea. Treatment with antibiotics is a better alternative. Antibiotic treatment varies depending on the cause of the acute diarrhea. Enhanced defensive and prophylactic measures will be needed until newer
antibiotics become available and the sanitation and hygiene in developing countries improve.

Authors: Papudesi Alekhya, Lomati Venkata Pavan Kumar Reddy*, Kanala Siva Kumar Reddy, Anga Samson Deepak, Languluri Reddenna

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