Rare Diseases

Strongyloidiasis after corticosteroid therapy: A case report


Introduction: Strongyloidiasis is a parasitic infection which can be divided into asymptomatic carriage, intestinal disease, hyperinfection with or without dissemination and it is also capable of a free living cycle. It is caused by Strongyloides stercoralis in humans. Generally in a healthy host, it is an asymptomatic infection but it causes hyper infection involving multiple organs in immunocompromised patients.

Case Report: We report an intestinal strongyloidiasis hyper- infection in a chronic obstructive pulmonary disease (COPD) patient of 66 years old. The patient had a history of receiving corticosteroid therapy frequently for acute exacerbations of COPD symptoms, during one of such episode the patient presented to our center, after receiving corticosteroid therapy the patient recovered from the episode but developed diarrhea, investigations done for diarrhea evaluation revealed larvae of Strongyloides in stool sample. Anthelmintic therapy, albendazole for three days followed by ivermectin for five days were given, the frequency of stools decreased to a great extent even though not completely cured.

Conclusion: Strongyloidiasis a helminthic infection common in southeast asia and other sub Saharan countries, the longevity of this infection is for decades due to autoinfection so, regular screening for this parasite in Immunocompromised patients should be done.

Authors: Jangala Mohan Sidhartha, Barabari Man Mohan, Maddinani Penchalaiah, Lomati Venkata Pavan Kumar Reddy

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